Glucagon Kit
Product Images NDC 51662-1498

Glucagon for Injection is a medication used to treat severe low blood sugar. A randomized clinical study was conducted on 31 healthy individuals who were administered a single subcutaneous injection of 1mg Glucagon for Injection. Adverse reactions were reported in at least 5% of the patients and the most common reactions were injection site swelling, injection site erythema, vomiting, nausea, decreased blood pressure, asthenia, headache, dizziness, pallor, diarrhea, and somnolence. In the previous study, where 29 patients were considered, nausea and vomiting were the most common outcomes.*

The text provides information regarding the recovery from insulin-induced hypoglycemia using a glucagon injection product in Type I diabetic men. The text includes a table with pharmacodynamic properties of the glucagon product for intravenous and intramuscular administration, including the time of maximal glucose concentration, time of onset of action, and duration of relaxation for GI smooth muscles. The dose for the injection is determined based on the length of the procedure.*

Table 3 provides information on clinically significant drug interactions with Glucagon for Injection. Beta-blockers can cause a temporary increase in blood pressure and heart rate. Indomethacin may reduce the ability of Glucagon for Injection to raise blood glucose or result in low blood sugar. The use of anticholinergic drugs combined with Glucagon for Injection increases the risk of gastrointestinal adverse reactions. Warfarin may be more effective when taken alongside Glucagon for Injection. Insulin may have an antagonistic effect when Glucagon for Injection is used as a diagnostic aid. It is important to monitor patients for any unusual bruising or bleeding, and adjust medication dosage as needed.*

This text describes different products containing Glucagon, used for the treatment of severe hypoglycemia or as a diagnostic aid. The first product presented is a kit for low blood sugar containing one single-dose vial of Glucagon and one single-dose syringe of sterile water for injection. The other two products are diagnostic kits containing 10 or 13 single-dose vials of Glucagon each, as well as a single-dose vial of sterile water for injection for reconstitution. No other relevant information is available.*

This text describes a list of symptoms that can be caused by hypoglycemia, including sweating, drowsiness, dizziness, sleep disturbances, irregular heartbeat (palpitations), anxiety, tremor, blurred vision, hunger, slurred speech, restlessness, depressed mood, tingling in the hands, feet, lips, or tongue, irritability, abnormal behavior, lightheadedness, unsteady movement, inability to concentrate, personality changes, and headache. It warns that if hypoglycemia is not treated early, it can worsen and the person may have severe symptoms such as confusion, unconsciousness, seizures, or even death.*

This is a description for a Glucagon Emergency Kit for Low Blood Sugar. The kit contains one single-dose vial of Glucagon for Injection with one milligram of medication, and a prefilled syringe with one mL of sterile water for injection (diluent). The medication should be reconstituted with the diluent immediately before use. It is meant for subcutaneous, intramuscular, or intravenous injection.*

This is a description for a single-dose syringe manufactured by Fresenius Kabi. The syringe has a capacity of 1 mL and is marked for volumes of 0.5 mL and 1 mL. It contains sterile water for injection, USP, and is intended for use as a drug diluent only.*

Glucagon 5% injection is a synthetic drug used for subcutaneous, intramuscular, or intravenous injection. It comes in a 1mg per vial formulation and should be reconstituted with sterile water for injection, USP. This drug contains glucagon hydrochloride 1mg and the lot/exp information is not available.*