Prolia Injection
Pricing Report NDC 55513-710-21
Current NADAC: $1,863.72296 per ML · Effective Aug 19, 2026
Current Package Pricing Information
The current wholesale acquisition cost for Prolia (NDC 55513-710-21) is $1863.72296 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 19, 2026.
As a a human prescription drug provided by Amgen, Inc, this medication is distributed in a 1 SYRINGE in 1 CARTON / 1 mL in 1 SYRINGE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $1,863.72296 Per ML
Pricing Unit
Effective Date
Aug 19, 2026
Data Status
As of Sep 09, 2026
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The NADAC was calculated based on package size.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Jul 2013, the NADAC wholesale price for (NDC ) has moved within a range of $816.11650 to $1,865.27280 per ML. Over this 13 years period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$816.1165 - $1,865.2728
$816.1165 - $1,865.2728
Market Volatility
128.55% Variance
128.55% Variance
Latest Trend
No Change
No Change
Recent NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Aug 19, 2026 | $1863.72296 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 19, 2026 | $1863.72296 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 22, 2026 | $1863.71755 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 22, 2026 | $1863.71755 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 17, 2026 | $1864.63390 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 17, 2026 | $1864.63390 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 20, 2026 | $1865.27280 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 20, 2026 | $1865.27280 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 07, 2026 | $1863.95096 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 07, 2026 | $1863.95096 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 07, 2026 | $1863.95096 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 07, 2026 | $1863.95096 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
Earlier NADAC Price History
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Jan 07, 2026 | $1863.95096 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 07, 2026 | $1863.95096 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 17, 2025 | $1809.66113 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 17, 2025 | $1809.66113 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 19, 2025 | $1809.63498 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 19, 2025 | $1809.63498 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 22, 2025 | $1809.64733 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 22, 2025 | $1809.64733 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 17, 2025 | $1809.19472 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 17, 2025 | $1809.19472 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2025 | $1809.55023 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Aug 20, 2025 | $1809.55023 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 23, 2025 | $1808.85800 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jul 23, 2025 | $1808.85800 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 18, 2025 | $1809.25443 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jun 18, 2025 | $1809.25443 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 21, 2025 | $1811.03521 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 21, 2025 | $1811.03521 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 08, 2025 | $1809.87494 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 08, 2025 | $1809.87494 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 08, 2025 | $1809.87494 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 08, 2025 | $1809.87494 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 08, 2025 | $1809.87494 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 08, 2025 | $1809.87494 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Nov 20, 2024 | $1723.69042 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 20, 2024 | $1723.69042 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Nov 20, 2024 | $1723.69042 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 20, 2024 | $1723.69042 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Oct 30, 2024 | $1725.39901 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 27, 2024 | $1725.39901 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 27, 2024 | $1725.39901 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jun 27, 2024 | $1725.39901 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 19, 2024 | $1677.58776 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| May 22, 2024 | $1678.16732 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Jan 05, 2024 | $1679.33308 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 05, 2024 | $1679.33308 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 05, 2024 | $1679.33308 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jun 30, 2023 | $1570.93834 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jun 30, 2023 | $1570.93834 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jun 30, 2023 | $1570.93834 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 04, 2023 | $1512.69941 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 04, 2023 | $1512.69941 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 04, 2023 | $1512.69941 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jul 01, 2022 | $1428.42248 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 01, 2022 | $1428.42248 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 01, 2022 | $1428.42248 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jan 26, 2022 | $1386.81794 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 26, 2022 | $1386.81794 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 26, 2022 | $1386.81794 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Nov 17, 2021 | $1309.55424 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Nov 17, 2021 | $1309.55424 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 22, 2021 | $1307.49746 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 22, 2021 | $1307.49746 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 22, 2021 | $1307.49746 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Sep 23, 2020 | $1234.65294 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Sep 23, 2020 | $1234.65294 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Apr 22, 2020 | $1237.68279 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Apr 22, 2020 | $1237.68279 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 17, 2020 | $1234.02836 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 17, 2020 | $1234.02836 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 17, 2020 | $1234.02836 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Dec 18, 2019 | $1176.38548 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Dec 18, 2019 | $1176.38548 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 17, 2019 | $1178.51504 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 17, 2019 | $1178.51504 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 17, 2019 | $1178.51504 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Oct 17, 2018 | $1144.18935 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Oct 17, 2018 | $1144.18935 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 18, 2018 | $1143.07772 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 18, 2018 | $1143.07772 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 18, 2018 | $1143.07772 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jul 20, 2017 | $1089.62092 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 20, 2017 | $1089.62092 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 20, 2017 | $1089.62092 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Feb 22, 2017 | $1040.70766 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Feb 22, 2017 | $1040.70766 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 13, 2017 | $1051.13287 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 21, 2016 | $1002.01413 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 21, 2016 | $1002.01413 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 21, 2016 | $1002.01413 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Mar 23, 2016 | $973.77467 | ML | C/I - Chain or Independent Pharmacy | Code 1, 5 | B - Brand |
| Mar 23, 2016 | $973.77467 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 14, 2016 | $969.04962 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 14, 2016 | $969.04962 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 16, 2015 | $923.76659 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 16, 2015 | $923.76659 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 15, 2015 | $897.70618 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 15, 2015 | $897.70618 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jul 11, 2014 | $855.77329 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jul 11, 2014 | $855.77329 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 10, 2014 | $831.64720 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
| Jan 10, 2014 | $831.64720 | ML | C/I - Chain or Independent Pharmacy | Code 3, 5 | B - Brand |
| Jan 10, 2014 | $831.64720 | ML | C/I - Chain or Independent Pharmacy | Code 4, 5 | B - Brand |
| Jul 26, 2013 | $816.11650 | ML | C/I - Chain or Independent Pharmacy | Code 2, 5 | B - Brand |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
- Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: September 09, 2026
