Prolia Injection
Pricing Report NDC 55513-710-21

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Prolia (NDC 55513-710-21) is $1864.63390 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Amgen, Inc, this medication is distributed in a 1 SYRINGE in 1 CARTON / 1 mL in 1 SYRINGE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1,864.63390
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jun 17, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
1 SYRINGE in 1 CARTON / 1 mL in 1 SYRINGE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jul 2013, the NADAC wholesale price for (NDC ) has moved within a range of $816.11650 to $1,865.27280 per ML. Over this 12 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$816.1165 - $1,865.2728
Market Volatility
128.55% Variance
Latest Trend
0.03%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $1864.63390 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 17, 2026 $1864.63390 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $1865.27280 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $1865.27280 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 07, 2026 $1863.95096 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 07, 2026 $1863.95096 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 07, 2026 $1863.95096 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 07, 2026 $1863.95096 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 07, 2026 $1863.95096 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 07, 2026 $1863.95096 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $1809.66113 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 17, 2025 $1809.66113 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $1809.63498 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $1809.63498 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $1809.64733 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $1809.64733 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $1809.19472 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $1809.19472 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $1809.55023 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $1809.55023 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $1808.85800 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $1808.85800 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $1809.25443 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $1809.25443 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $1811.03521 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $1811.03521 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 08, 2025 $1809.87494 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 08, 2025 $1809.87494 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 08, 2025 $1809.87494 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 08, 2025 $1809.87494 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 08, 2025 $1809.87494 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 08, 2025 $1809.87494 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 20, 2024 $1723.69042 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $1723.69042 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 20, 2024 $1723.69042 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $1723.69042 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Oct 30, 2024 $1725.39901 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 27, 2024 $1725.39901 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 27, 2024 $1725.39901 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jun 27, 2024 $1725.39901 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 19, 2024 $1677.58776 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $1678.16732 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 05, 2024 $1679.33308 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 05, 2024 $1679.33308 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 05, 2024 $1679.33308 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 30, 2023 $1570.93834 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 30, 2023 $1570.93834 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jun 30, 2023 $1570.93834 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 04, 2023 $1512.69941 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 04, 2023 $1512.69941 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 04, 2023 $1512.69941 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2022 $1428.42248 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2022 $1428.42248 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2022 $1428.42248 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 26, 2022 $1386.81794 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 26, 2022 $1386.81794 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 26, 2022 $1386.81794 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 17, 2021 $1309.55424 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 17, 2021 $1309.55424 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 22, 2021 $1307.49746 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 22, 2021 $1307.49746 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 22, 2021 $1307.49746 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 23, 2020 $1234.65294 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 23, 2020 $1234.65294 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Apr 22, 2020 $1237.68279 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 22, 2020 $1237.68279 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2020 $1234.02836 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2020 $1234.02836 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 17, 2020 $1234.02836 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2019 $1176.38548 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Dec 18, 2019 $1176.38548 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2019 $1178.51504 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2019 $1178.51504 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 17, 2019 $1178.51504 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 17, 2018 $1144.18935 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 17, 2018 $1144.18935 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 18, 2018 $1143.07772 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 18, 2018 $1143.07772 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 18, 2018 $1143.07772 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 20, 2017 $1089.62092 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 20, 2017 $1089.62092 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 20, 2017 $1089.62092 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 22, 2017 $1040.70766 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 22, 2017 $1040.70766 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 13, 2017 $1051.13287 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 21, 2016 $1002.01413 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 21, 2016 $1002.01413 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 21, 2016 $1002.01413 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Mar 23, 2016 $973.77467 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 23, 2016 $973.77467 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 14, 2016 $969.04962 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 14, 2016 $969.04962 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 16, 2015 $923.76659 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 16, 2015 $923.76659 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 15, 2015 $897.70618 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 15, 2015 $897.70618 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 11, 2014 $855.77329 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 11, 2014 $855.77329 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 10, 2014 $831.64720 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 10, 2014 $831.64720 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 10, 2014 $831.64720 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 26, 2013 $816.11650 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: June 17, 2026