Enbrel Solution
Pricing Report NDC 58406-010-04

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The latest wholesale acquisition cost for Enbrel (NDC 58406-010-04) is $2076.23080 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 07, 2026.

As a a human prescription drug provided by Immunex Corporation, this medication is distributed in a 4 SYRINGE in 1 CARTON / .5 mL in 1 SYRINGE (58406-010-01) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$2,076.23080
Per ML

Effective Date
Jan 07, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
4 SYRINGE in 1 CARTON / .5 mL in 1 SYRINGE (58406-010-01)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jan 2020, the NADAC wholesale price for (NDC ) has moved within a range of $1,261.82500 to $2,076.23080 per ML. Over this 5 years and 11 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$1,261.8250 - $2,076.2308
Market Volatility
64.54% Variance
Latest Trend
5.00%
Date Unit Price Unit Source Method Rate
Jan 07, 2026 $2076.23080 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 07, 2026 $2076.23080 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 07, 2026 $2076.23080 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $1977.36267 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $1978.01538 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $1977.14875 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $1980.13063 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $1980.40357 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $1979.06833 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $1977.19900 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 08, 2025 $1983.31341 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 08, 2025 $1983.31341 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 08, 2025 $1983.31341 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 23, 2024 $1853.56394 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 23, 2024 $1853.56394 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 23, 2024 $1853.56394 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 21, 2024 $1799.55917 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $1798.13192 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $1797.74833 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $1797.74833 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 05, 2024 $1801.41825 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 05, 2024 $1801.41825 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 05, 2024 $1801.41825 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 04, 2023 $1715.63643 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 04, 2023 $1715.63643 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 04, 2023 $1715.63643 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jul 01, 2022 $1597.42684 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2022 $1597.42684 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 26, 2022 $1559.98715 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 26, 2022 $1559.98715 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 26, 2022 $1559.98715 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 21, 2021 $1452.50200 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 21, 2021 $1452.50200 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Apr 21, 2021 $1452.50200 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 23, 2020 $1355.20005 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 23, 2020 $1355.20005 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 23, 2020 $1355.20005 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 22, 2020 $1261.82500 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026