Guaifenesin And Dextromethorphan Hydrobromide Syrup
Pricing Report NDC 58657-505-08

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Guaifenesin And Dextromethorphan Hydrobromide (NDC 58657-505-08) is $0.02517 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Apr 22, 2026.

As a a human over the counter drug provided by Method Pharmaceuticals, this medication is distributed in a 237 mL in 1 BOTTLE, PLASTIC configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.02517
Per ML

Effective Date
Apr 22, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
237 mL in 1 BOTTLE, PLASTIC
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2016, the NADAC wholesale price for (NDC ) has moved within a range of $0.00804 to $0.03072 per ML. Over this 9 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0080 - $0.0307
Market Volatility
282.09% Variance
Latest Trend
1.37%
Date Unit Price Unit Source Method Rate
Apr 22, 2026 $0.02517 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.02517 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Mar 18, 2026 $0.02483 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.02483 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.02449 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.02417 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.02417 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Aug 21, 2024 $0.02375 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.02205 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.02345 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.02345 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 17, 2024 $0.02290 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.03072 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.03072 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 17, 2023 $0.02494 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.02494 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Feb 22, 2023 $0.02786 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.02786 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 18, 2023 $0.02367 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.02343 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.02343 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Oct 19, 2022 $0.02139 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.02043 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.01331 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.01206 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.01442 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.01444 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.01352 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.01304 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.01313 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.01232 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.01046 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.01091 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.00889 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.01337 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.01159 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 21, 2021 $0.01170 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.01164 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 19, 2021 $0.01229 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 21, 2021 $0.01168 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 17, 2021 $0.01217 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2021 $0.01219 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 20, 2021 $0.01190 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $0.01145 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $0.01223 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $0.01230 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $0.01226 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.01237 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $0.01142 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2020 $0.01228 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2020 $0.01319 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $0.01188 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2020 $0.01199 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2020 $0.01172 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2020 $0.01150 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2019 $0.01314 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2019 $0.01200 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2019 $0.01045 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2019 $0.01243 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2019 $0.01207 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2019 $0.01146 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2019 $0.01201 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2019 $0.01040 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2019 $0.00997 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2019 $0.01018 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 20, 2019 $0.01033 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 23, 2019 $0.01023 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 19, 2018 $0.00960 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 21, 2018 $0.00968 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 17, 2018 $0.00991 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 19, 2018 $0.01013 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 22, 2018 $0.00978 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 18, 2018 $0.00958 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 20, 2018 $0.01008 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 23, 2018 $0.00993 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 18, 2018 $0.00989 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 21, 2018 $0.00986 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2018 $0.00974 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2018 $0.01014 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2017 $0.00968 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2017 $0.00954 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2017 $0.00969 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2017 $0.01011 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2017 $0.00941 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2017 $0.00944 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2017 $0.00957 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2017 $0.00947 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2017 $0.00970 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2017 $0.00966 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2017 $0.00975 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2017 $0.00981 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2016 $0.00926 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2016 $0.00821 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2016 $0.00864 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 12, 2016 $0.00804 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026