Benadryl Extra Strength Itch Relief Solution
NDC Package 69968-0459-1

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Benadryl Extra Strength Itch Relief (diphenhydramine hydrochloride and zinc acetate) solution is do not use more than directedhold stick straight down over affected skin areapress tip of stick repeatedly on affected skin area until liquid flows, then dab sparingly adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times dailychildren under 2 years of age: ask a doctor. This formulation utilizes a solution delivery system. Marketed by Kenvue Brands Llc, this product is identified by NDC 69968-0459 and is authorized under FDA application M017.

Identification & Billing

NDC Package Code
69968-0459-1
Package Description
1 APPLICATOR in 1 CARTON / 14 mL in 1 APPLICATOR
Product Code
69968-0459
11-Digit Billing Format
69968045901
Billing Unit
ML - Billing unit of "milliliter" is used when a product is measured by its liquid volume.
RxNorm Crosswalk
  • RxCUI: 1294589 - diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Solution
  • RxCUI: 1294589 - diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution
  • RxCUI: 1294589 - diphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Solution
  • RxCUI: 1294591 - Benadryl 2 % / 0.1 % Topical Solution
  • RxCUI: 1294591 - diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Solution [Benadryl Itch Stopping]

Clinical Specifications

Proprietary Name
Benadryl Extra Strength Itch Relief
Non-Proprietary Name
Diphenhydramine Hydrochloride And Zinc Acetate
Substance Name
Diphenhydramine Hydrochloride; Zinc Acetate
Dosage Form
Solution - A clear, homogeneous liquid1 dosage form that contains one or more chemical substances dissolved in a solvent or mixture of mutually miscible solvents.
Administration Route
Topical - Administration to a particular spot on the outer surface of the body. The E2B term TRANSMAMMARY is a subset of the term TOPICAL.
Active Ingredient(s)
Pharmacologic Class
Usage Information
Do not use more than directedhold stick straight down over affected skin areapress tip of stick repeatedly on affected skin area until liquid flows, then dab sparingly adults and children 2 years of age and older: apply to affected area not more than 3 to 4 times dailychildren under 2 years of age: ask a doctor

Regulatory & Marketing

Labeler Name
Kenvue Brands Llc
Product Type
Human Otc Drug
FDA Application #
M017
Marketing Category
OTC MONOGRAPH DRUG -
Start Marketing Date
06-01-2019
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 69968-0459-1 identifies a specific commercial package of 1 applicator in 1 carton / 14 ml in 1 applicator of Benadryl Extra Strength Itch Relief, a human over the counter drug labeled by Kenvue Brands Llc. This solution is formulated for topical use and contains diphenhydramine hydrochloride; zinc acetate as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Kenvue Brands Llc on June 01, 2019. The current certification is valid through December 31, 2026.

How is this Kenvue Brands Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 69968045901. Quantities are measured in per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-4-1)
69968-0459-1
11-Digit CMS (5-4-2)
69968-0459-01

Note: The zero is added to the Package segment to maintain the 5-4-2 structure.