Amazon Solution
NDC Package 72288-587-04

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Amazon (dextromethorphan hbr, doxylamine succinate) solution is ▪measure only with dosing cup provided▪keep dosing cup with product▪mL = milliliter▪do not take more than 4 doses in any 24-hour period▪this adult product is not intended for use in children under 12 years of ageagedoseadults and children 12 years and over20 ml every 6 hourschildren under 12 yearsdo not use. This formulation utilizes a solution delivery system. Marketed by Amazon.com Services Llc, this product is identified by NDC 72288-587 and is authorized under FDA application M012.

Identification & Billing

NDC Package Code
72288-587-04
Package Description
1 BOTTLE in 1 CARTON / 118 mL in 1 BOTTLE
Product Code
72288-587
11-Digit Billing Format
72288058704
RxNorm Crosswalk
  • RxCUI: 1115329 - dextromethorphan HBr 30 MG / doxylamine succinate 12.5 MG in 20 mL Oral Solution
  • RxCUI: 1115329 - dextromethorphan hydrobromide 1.5 MG/ML / doxylamine succinate 0.625 MG/ML Oral Solution
  • RxCUI: 1115329 - dextromethorphan hydrobromide 30 MG / doxylamine succinate 12.5 MG per 20 ML Oral Solution
  • RxCUI: 1115329 - dextromethorphan hydrobromide 7.5 MG / doxylamine succinate 3.125 MG per 5 ML Oral Solution

Clinical Specifications

Proprietary Name
Amazon Maximim Strength Adult Nighttime Cough Dm
Non-Proprietary Name
Dextromethorphan Hbr, Doxylamine Succinate
Substance Name
Dextromethorphan Hydrobromide; Doxylamine Succinate
Dosage Form
Solution - A clear, homogeneous liquid1 dosage form that contains one or more chemical substances dissolved in a solvent or mixture of mutually miscible solvents.
Administration Route
Oral - Administration to or by way of the mouth.
Active Ingredient(s)
Pharmacologic Class
Usage Information
▪measure only with dosing cup provided▪keep dosing cup with product▪mL = milliliter▪do not take more than 4 doses in any 24-hour period▪this adult product is not intended for use in children under 12 years of ageagedoseadults and children 12 years and over20 ml every 6 hourschildren under 12 yearsdo not use

Regulatory & Marketing

Labeler Name
Amazon.com Services Llc
Product Type
Human Otc Drug
FDA Application #
M012
Marketing Category
OTC MONOGRAPH DRUG -
Start Marketing Date
02-16-2026
Listing Expiration
12-31-2027
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 72288-587-04 identifies a specific commercial package of 1 bottle in 1 carton / 118 ml in 1 bottle of Amazon Maximim Strength Adult Nighttime Cough Dm, a human over the counter drug labeled by Amazon.com Services Llc. This solution is formulated for oral use and contains dextromethorphan hydrobromide; doxylamine succinate as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Amazon.com Services Llc on February 16, 2026. The current certification is valid through December 31, 2027.

How is this Amazon.com Services Llc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 72288058704. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
72288-587-04
11-Digit CMS (5-4-2)
72288-0587-04

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.