Tyrvaya Spray
Pricing Report NDC 73521-030-02

Current NADAC: $79.62813 per ML · Effective Sep 23, 2026 · Est. package price $668.88 (8.4 ML)
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

The current wholesale acquisition cost for Tyrvaya (NDC 73521-030-02) is $79.62813 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Sep 23, 2026.

As a a human prescription drug provided by Oyster Point Pharma, Inc., this medication is distributed in a 2 BOTTLE, PUMP in 1 CARTON / 4.2 mL in 1 BOTTLE, PUMP configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$79.62813
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Sep 23, 2026
Billable Units
8.4 ML
Estimated Package Price
$668.88
Data Status
As of Oct 07, 2026
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
B - Brand
Package NDC
73521-030-02
Description
2 BOTTLE, PUMP in 1 CARTON / 4.2 mL in 1 BOTTLE, PUMP
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2022, the NADAC wholesale price for (NDC ) has moved within a range of $67.74127 to $79.64275 per ML. Over this 4 years and 1 month period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$67.7413 - $79.6428
Market Volatility
17.57% Variance
Latest Trend
0.04%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Sep 23, 2026 $79.62813 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 19, 2026 $79.59960 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 22, 2026 $79.60577 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 17, 2026 $79.63687 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $79.64275 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2026 $79.56294 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $79.56294 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Dec 17, 2025 $78.00289 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $77.99421 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $78.03915 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $78.02006 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $78.00565 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: October 07, 2026