Tyrvaya Spray
Pricing Report NDC 73521-030-02

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Tyrvaya (NDC 73521-030-02) is $79.63687 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Oyster Point Pharma, Inc., this medication is distributed in a 2 BOTTLE, PUMP in 1 CARTON / 4.2 mL in 1 BOTTLE, PUMP configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$79.63687
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
2 BOTTLE, PUMP in 1 CARTON / 4.2 mL in 1 BOTTLE, PUMP
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Aug 2022, the NADAC wholesale price for (NDC ) has moved within a range of $67.74127 to $79.64275 per ML. Over this 3 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$67.7413 - $79.6428
Market Volatility
17.57% Variance
Latest Trend
0.01%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $79.63687 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $79.64275 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2026 $79.56294 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $79.56294 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Dec 17, 2025 $78.00289 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $77.99421 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $78.03915 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $78.02006 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $78.00565 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $77.94864 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $77.97602 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $77.99448 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 07, 2025 $78.36419 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 07, 2025 $78.36419 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 07, 2025 $78.36419 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2024 $76.08174 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $76.09478 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $76.12181 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $76.15855 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $76.22884 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $76.15182 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $76.20940 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $76.29460 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 19, 2024 $76.16865 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 19, 2024 $76.16865 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 19, 2024 $76.16865 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 18, 2023 $72.54226 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 18, 2023 $72.54226 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 13, 2023 $72.48316 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 13, 2023 $72.48316 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 13, 2023 $72.48316 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Aug 17, 2022 $67.74127 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 17, 2022 $67.74127 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026