Avzivi Injection, Solution
NDC Package 82143-002-01

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Avzivi (bevacizumab-tnjn) injection is none. This formulation utilizes a injection, solution delivery system. Marketed by Bio-thera Solutions, Ltd., this product is identified by NDC 82143-002 and is authorized under FDA application BLA761198.

Identification & Billing

NDC Package Code
82143-002-01
Package Description
1 VIAL in 1 CARTON / 16 mL in 1 VIAL
Product Code
82143-002
11-Digit Billing Format
82143000201
RxNorm Crosswalk

Clinical Specifications

Proprietary Name
Avzivi
Non-Proprietary Name
Bevacizumab-tnjn
Substance Name
Bevacizumab-tnjn
Dosage Form
Injection, Solution - A liquid preparation containing one or more drug substances dissolved in a suitable solvent or mixture of mutually miscible solvents that is suitable for injection.
Administration Route
Intravenous - Administration within or into a vein or veins.
Active Ingredient(s)
BEVACIZUMAB-TNJN 400 mg/16mL
Pharmacologic Class
Usage Information
None.

Regulatory & Marketing

Labeler Name
Bio-thera Solutions, Ltd.
Product Type
Human Prescription Drug
FDA Application #
BLA761198
Marketing Category
BLA - A product marketed under an approved Biologic License Application.
Start Marketing Date
01-01-2025
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 82143-002-01 identifies a specific commercial package of 1 vial in 1 carton / 16 ml in 1 vial of Avzivi, a human prescription drug labeled by Bio-thera Solutions, Ltd.. This injection, solution is formulated for intravenous use and contains bevacizumab-tnjn as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Bio-thera Solutions, Ltd. on January 01, 2025. The current certification is valid through December 31, 2026.

How is this Bio-thera Solutions, Ltd. product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 82143000201. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
82143-002-01
11-Digit CMS (5-4-2)
82143-0002-01

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.