Pulmozyme Solution
Pricing Report NDC 50242-100-40

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for Pulmozyme (NDC 50242-100-40) is $53.12202 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human prescription drug provided by Genentech, Inc., this medication is distributed in a 5 POUCH in 1 CARTON / 6 AMPULE in 1 POUCH (50242-100-39) / 2.5 mL in 1 AMPULE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$53.12202
Per ML

Effective Date
Jun 17, 2026
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
5 POUCH in 1 CARTON / 6 AMPULE in 1 POUCH (50242-100-39) / 2.5 mL in 1 AMPULE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Feb 2013, the NADAC wholesale price for (NDC ) has moved within a range of $30.65454 to $53.25043 per ML. Over this 13 years and 3 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$30.6545 - $53.2504
Market Volatility
73.71% Variance
Latest Trend
0.10%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $53.12202 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 20, 2026 $53.17627 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2026 $53.25043 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2026 $53.25043 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2026 $53.25043 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 17, 2025 $51.69945 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 19, 2025 $51.66091 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 22, 2025 $51.62316 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 17, 2025 $51.56663 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 20, 2025 $51.55798 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 23, 2025 $51.54088 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 18, 2025 $51.49092 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 21, 2025 $51.37117 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2025 $51.66443 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2025 $51.66443 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2025 $51.66443 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 18, 2024 $50.15964 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 20, 2024 $50.23847 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 23, 2024 $50.27459 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Sep 18, 2024 $50.22657 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 21, 2024 $50.28677 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2024 $50.28061 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2024 $50.26202 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
May 22, 2024 $50.23305 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 01, 2024 $50.48923 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2024 $50.48923 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2024 $50.48923 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2023 $49.01867 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2023 $49.01867 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2023 $49.01867 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 01, 2022 $46.90782 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Apr 01, 2022 $46.90782 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Apr 01, 2022 $46.90782 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Feb 23, 2022 $44.67411 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 23, 2022 $44.67411 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Oct 20, 2021 $44.80988 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 20, 2021 $44.80988 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 21, 2021 $44.58010 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 21, 2021 $44.58010 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 21, 2021 $44.58010 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 21, 2021 $44.48147 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 21, 2021 $44.48147 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Apr 21, 2021 $44.48147 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 17, 2020 $44.53080 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 17, 2020 $44.53080 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 17, 2020 $44.53080 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Apr 22, 2020 $44.32212 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Apr 22, 2020 $44.32212 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 17, 2019 $44.61375 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jul 17, 2019 $44.61375 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Mar 13, 2019 $44.79277 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Mar 13, 2019 $44.79277 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Aug 22, 2018 $44.44347 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Aug 22, 2018 $44.44347 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Aug 15, 2018 $44.40614 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jun 20, 2018 $44.25172 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 20, 2018 $44.25172 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2018 $44.62033 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2018 $44.62033 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2018 $44.62033 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Dec 20, 2017 $42.49556 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 22, 2017 $42.34969 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 01, 2017 $42.35999 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Mar 22, 2017 $42.01749 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 22, 2017 $42.01749 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Feb 22, 2017 $42.05593 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 01, 2017 $42.32448 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2017 $42.32448 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Mar 23, 2016 $39.55559 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 23, 2016 $39.55559 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2016 $39.48067 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 01, 2016 $39.48067 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Oct 21, 2015 $36.22079 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Oct 21, 2015 $36.22079 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 05, 2015 $36.42066 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 05, 2015 $36.42066 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 03, 2014 $33.41345 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 03, 2014 $33.41345 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Dec 18, 2013 $30.65454 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Feb 21, 2013 $30.98573 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026