M-dryl Liquid
Pricing Report NDC 58657-528-16

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

The current wholesale acquisition cost for M-dryl (NDC 58657-528-16) is $0.01702 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jun 17, 2026.

As a a human over the counter drug provided by Method Pharmaceuticals, Llc, this medication is distributed in a 473 mL in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.01702
Per ML

Effective Date
Jun 17, 2026
Billable Units
473 ML
Estimated Package Price
$8.05
Data Status
As of Jul 08, 2026
C/I - Chain or Independent Pharmacy
Package NDC
Description
473 mL in 1 BOTTLE
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2019, the NADAC wholesale price for (NDC ) has moved within a range of $0.00669 to $0.02819 per ML. Over this 6 years and 8 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.0067 - $0.0282
Market Volatility
321.38% Variance
Latest Trend
0.35%
Date Unit Price Unit Source Method Rate
Jun 17, 2026 $0.01994 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2026 $0.01702 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.01987 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2026 $0.01714 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.01943 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2026 $0.01677 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.01916 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2026 $0.01686 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.01867 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 18, 2026 $0.01713 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.01832 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 21, 2026 $0.01784 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.01752 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 17, 2025 $0.01595 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.01725 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 19, 2025 $0.01447 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.01748 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 22, 2025 $0.01233 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.01797 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 17, 2025 $0.01272 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.01810 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 20, 2025 $0.01223 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.01787 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 23, 2025 $0.01270 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.01725 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 18, 2025 $0.01210 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.01716 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 21, 2025 $0.01241 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.01736 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 23, 2025 $0.01214 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.01723 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 19, 2025 $0.01253 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.01697 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2025 $0.01202 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 12, 2025 $0.01642 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.02742 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2025 $0.01189 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.02761 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2024 $0.01208 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.02735 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 20, 2024 $0.01182 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.02802 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 23, 2024 $0.01290 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.02800 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 18, 2024 $0.01208 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.02786 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 21, 2024 $0.01281 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.02721 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 17, 2024 $0.01228 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.02819 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 19, 2024 $0.01277 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 22, 2024 $0.01383 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.02815 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 17, 2024 $0.02815 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Apr 17, 2024 $0.01319 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 20, 2024 $0.01217 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 21, 2024 $0.01670 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 17, 2024 $0.01388 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 20, 2023 $0.01391 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 22, 2023 $0.01300 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 18, 2023 $0.01282 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 20, 2023 $0.01563 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 23, 2023 $0.01439 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 19, 2023 $0.01630 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 21, 2023 $0.01387 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 17, 2023 $0.01526 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 19, 2023 $0.02041 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 22, 2023 $0.02435 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 22, 2023 $0.01771 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 18, 2023 $0.01508 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 21, 2022 $0.01139 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 23, 2022 $0.01406 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 19, 2022 $0.01691 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 21, 2022 $0.01359 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 17, 2022 $0.01638 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 20, 2022 $0.02002 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 22, 2022 $0.01754 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 18, 2022 $0.01411 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 20, 2022 $0.02402 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 23, 2022 $0.02458 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 23, 2022 $0.02321 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 19, 2022 $0.01773 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 22, 2021 $0.02281 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 17, 2021 $0.01589 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 20, 2021 $0.01373 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 22, 2021 $0.01900 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 18, 2021 $0.02031 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.01865 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 23, 2021 $0.01865 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
May 19, 2021 $0.01994 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 21, 2021 $0.01753 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2021 $0.02395 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 17, 2021 $0.02395 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic
Jan 20, 2021 $0.02262 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 23, 2020 $0.02232 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Nov 18, 2020 $0.02267 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 21, 2020 $0.02270 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Sep 23, 2020 $0.02000 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Aug 19, 2020 $0.01435 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jul 22, 2020 $0.01986 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jun 17, 2020 $0.02200 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
May 20, 2020 $0.02428 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Apr 22, 2020 $0.01770 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Mar 18, 2020 $0.02317 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Feb 19, 2020 $0.02774 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Jan 22, 2020 $0.02415 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Dec 18, 2019 $0.02725 MLC/I - Chain or Independent PharmacyCode 1, 5G - Generic
Oct 09, 2019 $0.00669 MLC/I - Chain or Independent PharmacyCode 4, 5G - Generic

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026