Desflurane Liquid
NDC Package 66794-021-25

View Billable Units, 11-Digit Conversion Format, and RxNorm mappings
Table of Contents
    1. Package Information
    2. Frequently Asked Questions

Package Information

Desflurane liquids is the use of Desflurane is contraindicated in the following conditions:• Known or suspected genetic susceptibility to malignant hyperthermia [see Warnings and Precautions ( 5.1), Clinical Pharmacology ( 12.5)]. This formulation utilizes a liquid delivery system. Marketed by Piramal Critical Care Inc, this product is identified by NDC 66794-021.

Identification & Billing

NDC Package Code
66794-021-25
Package Description
250 mL in 1 BOTTLE, GLASS
Product Code
66794-021
11-Digit Billing Format
66794002125
RxNorm Crosswalk

Clinical Specifications

Proprietary Name
Desflurane
Non-Proprietary Name
Desflurane
Substance Name
Desflurane
Dosage Form
Liquid - A dosage form consisting of a pure chemical in its liquid1 state. This dosage form term should not be applied to solutions.
Administration Route
Respiratory (inhalation) - Administration within the respiratory tract by inhaling orally or nasally for local or systemic effect.
Active Ingredient(s)
DESFLURANE 250 mL/250mL
Pharmacologic Class
Usage Information
The use of Desflurane is contraindicated in the following conditions:• Known or suspected genetic susceptibility to malignant hyperthermia [see Warnings and Precautions ( 5.1), Clinical Pharmacology ( 12.5)]. • Patients in whom general anesthesia is contraindicated.• Induction of anesthesia in pediatric patients.• Patients with known sensitivity to Desflurane, USP, Liquid for Inhalation or to other halogenated agents [ see Warnings and Precautions ( 5.5)]. • Patients with a history of moderate to severe hepatic dysfunction following anesthesia with Desflurane, USP, Liquid for Inhalation or other halogenated agents and not otherwise explained [ see Warnings and Precautions ( 5.5) ].

Regulatory & Marketing

Labeler Name
Piramal Critical Care Inc
Product Type
Human Prescription Drug
Marketing Category
UNAPPROVED DRUG OTHER - An unapproved drug product in a marketing category that is not reflected on a particular list.
Start Marketing Date
01-31-2026
Listing Expiration
12-31-2026
Exclude Flag
N
Sample Package
No

Hierarchy Structure

Code Lineage

The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

* Please review the full disclaimer at the bottom of this page.

Frequently Asked Questions

What is the distribution configuration for this product package?

The code 66794-021-25 identifies a specific commercial package of 250 ml in 1 bottle, glass of Desflurane, a human prescription drug labeled by Piramal Critical Care Inc. This liquid is formulated for respiratory (inhalation) use and contains desflurane as the active substance.

Is this product currently listed with the FDA?

Yes, this product is active and verified within the NDC Directory. It was introduced to the market by Piramal Critical Care Inc on January 31, 2026. The current certification is valid through December 31, 2026.

How is this Piramal Critical Care Inc product billed for insurance claims?

For medical billing and reimbursement, this package follows the 11-digit CMS format: 66794002125. The table below illustrates the segment conversion from the 10-digit labeler code to the 11-digit provider format.

11-Digit Code Conversion

Billing payers usually require a 5-4-2 segment configuration. Below is the conversion from the 10-digit package format to the 11-digit billing format:

10-Digit Format (5-3-2)
66794-021-25
11-Digit CMS (5-4-2)
66794-0021-25

Note: The zero is added to the Product segment to maintain the 5-4-2 structure.