NDC Package 16729-277-35 Methotrexate

Injection Intra-arterial; Intramuscular; Intrathecal; Intravenous - View Billable Units, 11-Digit Format, RxNorm

Package Information

Find all the important details about this NDC Package code, including the 11-Digit NDC Billing number, billing units, wholesale price, RxNorm crosswalk, active ingredients, pharmacologic clasess, etc.

NDC Package Code:
16729-277-35
Package Description:
1 VIAL in 1 CARTON / 40 mL in 1 VIAL
Product Code:
Proprietary Name:
Methotrexate
Non-Proprietary Name:
Methotrexate
Substance Name:
Methotrexate
Usage Information:
Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.
11-Digit NDC Billing Format:
16729027735
Billing Unit:
ML - Billing unit of "milliliter" is used when a product is measured by its liquid volume.
NDC to RxNorm Crosswalk:
  • RxCUI: 1655956 - methotrexate 1 GM in 40 ML Injection
  • RxCUI: 1655956 - 40 ML methotrexate 25 MG/ML Injection
  • RxCUI: 1655956 - methotrexate 1 GM per 40 ML Injection
  • RxCUI: 1655959 - methotrexate 250 MG in 10 ML Injection
  • RxCUI: 1655959 - 10 ML methotrexate 25 MG/ML Injection
  • Product Type:
    Human Prescription Drug
    Labeler Name:
    Accord Healthcare, Inc.
    Dosage Form:
    Injection - A sterile preparation intended for parenteral use; five distinct classes of injections exist as defined by the USP.
    Administration Route(s):
  • Intra-arterial - Administration within an artery or arteries.
  • Intramuscular - Administration within a muscle.
  • Intrathecal - Administration within the cerebrospinal fluid at any level of the cerebrospinal axis, including injection into the cerebral ventricles.
  • Intravenous - Administration within or into a vein or veins.
  • Active Ingredient(s):
    Sample Package:
    No
    FDA Application Number:
    ANDA040716
    Marketing Category:
    ANDA - A product marketed under an approved Abbreviated New Drug Application.
    Start Marketing Date:
    03-07-2014
    Listing Expiration Date:
    12-31-2024
    Exclude Flag:
    N
    Code Structure:

    The NDC Directory contains ONLY information on final marketed drugs submitted to FDA electronically by labelers. A labeler might be a manufacturer, re-packager or re-labeler. The product information included in the NDC directory does not indicate that FDA has verified the information provided by the product labeler. Assigned NDC numbers are not in any way an indication of FDA approval of the product.

    * Please review the disclaimer below.

    NDC HCPCS Crosswalk

    This crosswalk is intended to help the public understand which drug products (identified by NDCs) are assigned to which HCPCS billing codes.

    NDC 16729-277-35 HCPCS crosswalk information with package details and bill units information.

    NDC Billing CodeHCPCS CodeHCPCS Code Desc.DosagePackage SizePackage QuantityBillable UnitsBillable Units / Pkg
    16729027735J9250Methotrexate sodium inj5 MG401200200
    16729027735J9260Methotrexate sodium inj50 MG4012020

    * Please review the disclaimer below.

    Other Product Packages

    The following packages are also available for this product:

    NDC Package CodePackage Description
    16729-277-031 VIAL in 1 CARTON / 10 mL in 1 VIAL
    16729-277-301 VIAL in 1 CARTON / 2 mL in 1 VIAL

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    Frequently Asked Questions

    What is NDC 16729-277-35?

    The NDC Packaged Code 16729-277-35 is assigned to a package of 1 vial in 1 carton / 40 ml in 1 vial of Methotrexate, a human prescription drug labeled by Accord Healthcare, Inc.. The product's dosage form is injection and is administered via intra-arterial; intramuscular; intrathecal; intravenous form.

    Is NDC 16729-277 included in the NDC Directory?

    Yes, Methotrexate with product code 16729-277 is active and included in the NDC Directory. The product was first marketed by Accord Healthcare, Inc. on March 07, 2014 and its listing in the NDC Directory is set to expire on December 31, 2024 if the product is not updated or renewed by the manufacturer.

    What is the NDC billing unit for package 16729-277-35?

    The contents of this package are billed per "ml or milliliter", products billed per milliliter are usually products measured by liquid volume.

    What is the 11-digit format for NDC 16729-277-35?

    The 11-digit format is 16729027735. The 11-digit billing format might be required by the Centers for Medicare & Medicaid Services (CMS) and other payers in billing claim forms.

    This package code is originally configured in a 5-3-2 segment 10-digit format and by adding a zero within the original NDC package code we can obtain the converted 11-digit format in a 5-4-2 segment configuration. The table below shows the 11-digit code conversion:

    10-Digit Format10-Digit Original Code11-Digit Format11-Digit Code
    5-3-216729-277-355-4-216729-0277-35